Assessment of an IVP Treatment in Dogs with Acute Pancreatitis

Client Compensation:

This study provides the monitoring and recheck diagnostics required by the trial at no cost for the management of your dog's pancreatitis, and up to an additional $3,000 toward your dog's hospitalization.  Additionally, both the treatment with IVP and the placebo will be covered by the study.

Potential Medical Benefits:

Depending on the group your dog is assigned, they may receive a well-tolerated anti-inflammatory (e.g., IVP) that helps lower swelling and has been safe in healthy dogs. This medicine might help your dog feel better faster and spend less time in the hospital. The other group gets a "placebo," which is a safe substance that does not have medicine in it. 
Because this is a new study, we don't know for sure yet if the IVP will work for every dog, and the placebo itself doesn't provide a direct medical benefit. However, all dogs in the study, no matter which group they are in, will receive the best standard medical care from our team to treat their illness. Results from this study will not be available immediately.

Potential Medical Risks:

During your dogs hospitalization and on Day 14 Recheck, they will need to be held gently for a short time to have blood samples taken and to perform an abdominal/belly ultrasound. These are common procedures at our hospital and usually do not cause any pain or discomfort.  
While rare, some minor issues could happen, such as a small bruise (e.g., hematoma) where the blood was drawn or your dog feeling a bit stressed while being held for the ultrasound. There is also a risk that your dog's condition may not get better, or it could even get worse. Dogs will be observed closely for possible side effects or changes in their health, and appropriate medical care will be provided.

What qualifies my pet for enrollment?

Inclusion Criteria: 
Your dog may be able to join this study if they:
 

• Show at least 2 of these signs consistent with pancreatitis:
  • Vomiting, Anorexia, Lethargy, Abdominal Pain, or Diarrhea.
• Have been evaluated to ensure their sickness isn't caused by something else by performing the following tests:
  • Complete Blood Count (CBC), Biochemical Profile, Urinalysis, and Abdominal Ultrasound.
• Abdominal ultrasound exam shows pancreatitis.

Exclusion Criteria: 
Dogs that are found to meet any of the exclusion criteria are not able to enroll:
 

• Have taken medications such as corticosteroids, non-steroidal anti-inflammatory drugs, analgesics, anti-emetics, or antibiotics within 24 hours.
• Had abdominal/belly surgery within the last month.
• Might have a different medical problem that is causing their symptoms, such as:
  • Gastrointestinal foreign body, toxicity, enteropathy, hypoadrenocorticism, hepatopathy, nephropathy, neoplasia.
     

Diagnosis/Condition Being Studied: Acute Pancreatitis
 

Intervention to Be Studied: IVP (RABI-767)