Blue Buffalo Veterinary Clinical Trials Office
Advancing the Health of Animals and Humans
Blue Buffalo Veterinary Clinical Trials Office (BBVCTO) helps animals and people live longer, healthier lives by supporting research that evaluates new ways to prevent, diagnose, and treat disease.
Blue Buffalo Veterinary Clinical Trials Office name does not indicate support for, endorsement of, or use of Blue Buffalo products in clinical trials.
Established in 2007 and located within The Ohio State University Veterinary Medical Center (OSU-VMC), BBVCTO is one of the nation's largest and most experienced veterinary clinical trials programs. The office supports 30-50 clinical trials annually involving client-owned animals with naturally occurring diseases.
Research conducted through these studies has contributed to advances in the treatment of conditions including cancer, heart disease, kidney disease, and other serious illnesses affecting both animals and people.
BBVCTO collaborates with experts from The Ohio State University Medical Center, The Ohio State University Comprehensive Cancer Center - James Cancer Hospital, the Clinical and Translational Science Institute, Wright Center for Innovation in Biomedical Imaging, and Nationwide Children's to support translational research that benefits both veterinary and human medicine.
Additional Resources
Enroll Your Pet in a Clinical Trial
Every clinical trial begins with determining whether a patient may be eligible for a trial.
Clinical trials may provide access to innovative treatments, additional monitoring, and specialized veterinary expertise while contributing to future advances in animal and human health.
We are grateful to our patients and their families whose participation helps advance veterinary medicine and improve care for future generations of pets and people.
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Partner with BBVCTO
BBVCTO provides support for Clinical Investigators, Industry Sponsors, Referring Veterinarians, and Research Collaborators.
Whether you are conducting a clinical trial, referring a patient, seeking research resources, or exploring collaborative opportunities, our team can help connect you with the appropriate services and support.
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Publications and Research Impact
Veterinary clinical trials are an important driver of medical discovery. Findings from studies conducted through BBVCTO have contributed to advances in both veterinary and human medicine.
Our patients and their owners play a vital role in these discoveries. We invite you to explore our publication highlights and learn how participation in clinical research helps improve the health of future animal and human patients.
- Effect of a struvite dissolution diet in cats with naturally occurring struvite urolithiasis
- Amino acid status in dogs with protein‐losing nephropathy
- Assessment of compounded transdermal mirtazapine as an appetite stimulant in cats with chronic kidney disease
- Comparison of Computed Tomography and Ultrasound Techniques for Quantifying Canine Urinary Bladder Transitional Cell Carcinoma Tumor Volume
- Proliferative and Invasive Colorectal Tumors in Pet Dogs Provide Unique Insights into Human Colorectal Cancer
- Phase I/II evaluation of RV1001, a novel PI3Kδ inhibitor, in spontaneous canine lymphoma
- MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines
- Plasma cytokeratin‐18 concentrations as noninvasive biomarker of early gastrointestinal toxicosis in dogs receiving toceranib
- Consecutive day HSP90 inhibitor administration improves efficacy in murine models of KIT-driven malignancies and canine mast cell tumors
- KTN0158, a humanized anti-KIT monoclonal antibody, demonstrates biologic activity against both normal and malignant canine mast cells
- Safety and efficacy of targeted hyperthermia treatment utilizing gold nanorod therapy in spontaneous canine neoplasia
- Association of Vitamin D Metabolites with Parathyroid Hormone, Fibroblast Growth Factor‐23, Calcium, and Phosphorus in Dogs with Various Stages of Chronic Kidney Disease
- Dogs as a Model for Cancer
- A pilot study of toceranib/vinblastine therapy for canine transitional cell carcinoma
- A simplified method of walking track analysis to assess short-term locomotor recovery after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs
- Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma
- Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study
- The effects of preoperative oral administration of carprofen or tramadol on postoperative analgesia in dogs undergoing cutaneous tumor removal
- Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma